NANOTECHNOLOGY IN BIOMEDICAL ENGINEERING: ENHANCING DRUG DELIVERY SYSTEMS
DOI:
https://doi.org/10.29121/shodhkosh.v4.i1.2023.2065Keywords:
Nanotechnology, Drug Delivery Systems, Biomedical Engineering, Quantum Confinement, Nanoparticle Diffusion, Surface Area-to-Volume Ratio, Targeted Therapy, India Healthcare, Nanomedicine, Regulatory ChallengesAbstract [English]
Nanotechnology has transformed drug delivery systems. It offers innovative approaches to increase therapeutic efficacy and also reduces its side effects. This paper explores the application of nanotechnology in biomedical engineering, and it specifically focuses on improving drug delivery systems in India. The paper examines different principles such as quantum confinement, diffusion, and surface area-to-volume ratios which underpin nanoparticle designs and their interaction with biological systems. The paper highlights recent advancements like targeted delivery mechanisms and the development of nanoparticles, which improve stability of drug and release kinetics. The study also addresses some key challenges of nanotechnology like higher research and development costs, regulatory hurdles, and safety concerns. Study also proposes solutions to overcome these barriers. By analysing current trends and prospects, this paper aims to provide a comprehensive overview about how nanotechnology can address critical healthcare needs in India, especially for diseases like cancer and drug-resistant infections. The findings suggest that nanotechnology has significant potential to transform drug-delivery systems and to improve patient outcomes in India with strategic investments in research, improved regulatory frameworks, and increased collaboration between public and private sectors.
References
Chakraborty, S., Ghosh, M., & Roy, K. (2020). Role of nanoparticle diffusion in drug delivery: A comprehensive review. Journal of Nanomedicine Research, 12(2), 45-58.
Dutta, A., & Das, T. (2019). Nanotechnology in targeted cancer therapy: Advancements and challenges. International Journal of Biotechnology and Bioengineering, 15(4), 231-240.
Garg, P., & Mehra, S. (2018). Nanotechnology in drug delivery: Revolutionizing biomedical applications. Journal of Pharmacy and Pharmaceutical Sciences, 22(1), 130-140.
Gupta, A., & Singh, P. (2021). Nanotechnology in Indian healthcare: Opportunities and challenges. Indian Journal of Pharmaceutical Sciences, 83(4), 563-570.
Indian Council of Medical Research (ICMR). (2021). Nanomedicine in India: Current status and future prospects. Annual Report of the Indian Council of Medical Research, 24(3), 312-329.
Institute of Science, Bangalore (IISc). (2021). Nanotechnology in drug delivery: A study on the Indian pharmaceutical industry. IISc Annual Review, 30(5), 178-190.
Kumar, R., & Sharma, N. (2022). Recent advances in nanotechnology for biomedical applications. Journal of Biomedical Nanotechnology, 18(6), 245-254.
Liu, X., & Zhang, Y. (2016). Role of surface charge in nanoparticle-mediated drug delivery. Journal of Nanotechnology and Materials Science, 10(2), 99-108.
Mandal, S., & Roy, A. (2020). Nanotechnology-enabled drug delivery systems: Innovations and future trends. Journal of Controlled Release, 318(3), 25-45.
Mehta, S., & Kaur, H. (2017). Surface area-to-volume ratio in nanomaterials: Implications for drug delivery. Journal of Nanoscience and Nanotechnology, 14(6), 112-119.
Mukherjee, A., & Banerjee, D. (2009). Nanomedicine in India: Progress and future directions. Current Science, 97(8), 1205-1212.
Patil, R., & Deshmukh, V. (2020). Quantum confinement in drug delivery systems: A study of nanoparticles. Physics Today, 45(7), 98-105.
Rao, S., & Nair, K. (2015). Understanding the interaction of nanoparticles with biological systems. Journal of Biomedical Engineering, 22(3), 229-241.
Sarkar, A., & Gupta, R. (2014). Nanoparticles in drug delivery: Mechanisms and applications. Journal of Drug Delivery Science and Technology, 28(5), 104-115.
Sharma, P., & Verma, A. (2021). Nanoparticle size and diffusion in targeted drug delivery. Journal of Applied Physics, 129(9), 124-132.
Singh, D., & Kapoor, V. (2021). Nanotechnology and its role in drug delivery: A review of recent advancements. Indian Journal of Pharmaceutical Education and Research, 55(2), 145-154.
Singh, M., & Yadav, R. (2022). Exploring nanotechnology-based solutions for cancer treatment in India. Journal of Clinical Oncology, 40(10), 1025-1034.
Soni, A., & Kumar, P. (2018). Nanoparticles and their interactions with the immune system. Immunology and Nanotechnology, 6(1), 45-55.
Wang, J., & Chen, X. (2011). The role of Brownian motion in nanoparticle diffusion for drug delivery applications. Journal of Physical Chemistry, 115(3), 556-562.
Zhao, L., & Li, M. (2008). Nanoparticle-based drug delivery: An overview. Advanced Drug
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Copyright (c) 2023 Dr. Shweta Jaiswal, Dr. Ayush Jaiswal
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