LIPID ABNORMALITY IN HYPERTENSIVE SUDANESE PATIENTS IN SHENDI LOCALITY, SUDAN

Authors

  • Eltigani MA Department of biochemistry
  • Barri AM Department of biochemistry
  • Khalid Hussein Bakheit Department of biochemistry, Faculty of Medicine, University of Tabuk, Tabuk, SAUDI ARABIA
  • Haghamad Allzain Department of biochemistry
  • Hijazi Mohamed Ahmed Department of Nursing
  • Ibrahim Bakhit Department of histopathology, Faculty of Medicine, Shendi University, Shendi, SUDAN
  • Rashid Eltayeb Department of biochemistry

DOI:

https://doi.org/10.29121/granthaalayah.v3.i6.2015.2994

Keywords:

Hypertension, Lipid Profile, Dyslipidemia, Cardiovascular Risk Factors, Cardiovascular Disease

Abstract [English]

Hypertension is commonly associated with other cardiovascular risk factors, such as obesity, diabetes, and dyslipidaemia. The presence of these cardiovascular risk factors and the resulting endothelial dysfunction may play a role in the pathophysiology of hypertension. Dyslipidaemia, a strong predictor of cardiovascular disease.


 This cross-sectional study was conducted at Shendi locality from February 2011 to July 2012. The patients underwent a clinical assessment, which included history (a questionnaire) and clinical examination. 100 hypertensive patients. The age limits was 40 to 60 years.


There was sharp and definite increase in the percentage of patients having >200mg/dl total cholesterol after four years of diabetes mellitus from (28-34%) to (41%). There was a sharp increase in the percentage of patients having >150mg/dl of low density lipoproteins after 6 years of diabetes mellitus from(8-9%)  to (14.2%). There was also an increase in the percentage of patients having <160mg/dl of triglycerides after four years of diabetes mellitus from 53% to 61% of diabetes.

Downloads

Download data is not yet available.

References

Maton A. Human Biology and Health Englewood Cliffs, New Jersey: Prentice Hall; 1993.

McGill HC, Jr., McMahan CA, Zieske AW, et al. Associations of coronary heart disease risk factors with the intermediate lesion of atherosclerosis in youth. The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. ArteriosclerThrombVasc Biol. Aug 2000;20(8):1998-2004.

CDC, US. Chronic Disease Overview: Center for Disease control and Prevention 1999.

Department of Health, Executive Yuan, Taiwan. Health and Vital statistics-vital statistics2005.

Rainwater DL, McMahan CA, Malcom GT, et al. Lipid and apolipoprotein predictors of atherosclerosis in youth: apolipoprotein concentrations do not materially improve prediction of arterial lesions in PDAY subjects. The PDAY Research Group. ArteriosclerThrombVasc Biol. Mar 1999;19(3):753-761.

Ahmed AM et al. Pattern of hospital mortality among diabetic patients in Sudan. PractDiabInt March 2000; Vol. 17 No. 2. DOI: https://doi.org/10.1002/(SICI)1528-252X(200003/04)17:2<41::AID-PDI29>3.0.CO;2-S

Halperin RO. Dyslipidemia and the Risk of Incident Hypertension in Men.Hypertension 2006;47:45-50. DOI: https://doi.org/10.1161/01.HYP.0000196306.42418.0e

Oparil S, Zaman MA, Calhoun DA. Pathogenesis of hypertension. Ann Intern Med 2003;139:761–776. DOI: https://doi.org/10.7326/0003-4819-139-9-200311040-00011

Castelli WP, Anderson K. A population at risk. Prevalence of high cholesterol levels in hypertensive patients in the Framingham Study. Am J Med 1986;80:23–32. DOI: https://doi.org/10.1016/0002-9343(86)90157-9

Anderson KM, Castelli WP, Levy D. Cholesterol and mortality. 30 years of follow-up from the Framingham study. JAMA 1987;257:2176 –2180. DOI: https://doi.org/10.1001/jama.1987.03390160062027

Gaziano JM, Sesso HD, Breslow JL, Hennekens CH, Buring JE. Relation between systemic hypertension and blood lipids on the risk of myocardial infarction. Am J Cardiol 1999;84:768 –773. DOI: https://doi.org/10.1016/S0002-9149(99)00435-X

Haffner SM, Miettinen H, Gaskill SP, Stern MP. Metabolic precursors of hypertension: the San Antonio Heart Study. Arch Intern Med 1996;156: 1994–2000. DOI: https://doi.org/10.1001/archinte.1996.00440160106013

Nohria A, Garrett L, Johnson W, Kinlay S, Ganz P, Creager MA. Endothelin-1 and vascular tone in subjects with atherogenic risk factors. Hypertension 2003;42:43– 48. DOI: https://doi.org/10.1161/01.HYP.0000074426.71392.D8

Dyslipidemia Can Promote Hypertension in Men. Available on: http://www.diabetesincontrol.com/articles/53-diabetes-news/3355- (Accessed on 24 January 2013).

Downloads

Published

2015-06-30

How to Cite

Eltigani, Barri, Bakheit, K. H., Allzain, H., Ahmed, H. M., Bakhit, I., & Eltayeb, R. (2015). LIPID ABNORMALITY IN HYPERTENSIVE SUDANESE PATIENTS IN SHENDI LOCALITY, SUDAN. International Journal of Research -GRANTHAALAYAH, 3(6), 1–6. https://doi.org/10.29121/granthaalayah.v3.i6.2015.2994

Most read articles by the same author(s)