CYTOMORPHOLOGICAL EVALUATION OF THYROID LESIONS USING THE BETHESDA SYSTEM: A STUDY OF 320 CASES
DOI:
https://doi.org/10.29121/shodhkosh.v7.i9s.2026.8072Keywords:
Thyroid Nodules, Fnac, Bethesda System, Thyroid Cytology, Thyroid LesionsAbstract [English]
Introduction: Thyroid nodules are common clinical findings and require accurate evaluation to differentiate benign from malignant lesions. Fine Needle Aspiration Cytology (FNAC) is widely used as a first-line diagnostic tool. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) provides a standardized reporting system.
Aim: To evaluate thyroid lesions using FNAC and classify them according to the Bethesda system.
Materials and Methods: This study included 320 patients presenting with thyroid swelling. FNAC was performed and smears were categorized according to the Bethesda system.
Results: Out of 320 cases, satisfactory cytological smears were obtained in 310 cases (96.8%) while 10 cases (3.1%) were non-diagnostic. The majority of cases belonged to Bethesda Category II (Benign) accounting for 89.3% cases. Category III (AUS) constituted 0.6% cases, Category IV (Follicular Neoplasm) 1.25%, Category V (Suspicious for Malignancy) 3.4%, and Category VI (Malignant) 2.18%.
Conclusion: FNAC using the Bethesda system is a reliable, simple, and cost‑effective diagnostic modality for the evaluation of thyroid lesions.
References
ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology.American journal of clinical pathology 2009 ;132(5):658-65. follow-up. J Cytol 2013;30(2):94-9. DOI: https://doi.org/10.1309/AJCPPHLWMI3JV4LA
Gritzmann N, Koischwitz D, Rettenbacher T. Sonography of the thyroid and parathyroid glands. Radiologic Clinics 2000;38(5):1131-145. DOI: https://doi.org/10.1016/S0033-8389(05)70225-6
Guhamallick M, Sengupta S, Bhattacharya NK, Basu N, Roy S, Ghosh AK, et al. Cytodiagnosis of thyroid lesions-usefulness and pitfalls: A study of 288 cases. J Cytol 2008;25(1):6-9. DOI: https://doi.org/10.4103/0970-9371.40650
Jo VY, Stelow EB, Dustin SM, Hanley KZ. Malignancy risk for fine needle aspiration of thyroid lesions according to the Bethesda System or Reporting Thyroid Cytopathology. Am J Clin Pathol 2010;134(3):450-6. DOI: https://doi.org/10.1309/AJCP5N4MTHPAFXFB
Mondal SK, Sinha S, Basak B, Roy DN, Sinha SK. The Bethesda system for reporting thyroid fine needle aspirates: A cytologic study with histologic
Mulje, M. D. (2026). Ai-Based Soil Health Analysis and Crop Recommendation System for Smart Fertilizer Management in Precision Agriculture. International Journal of Engineering Science Technologies, 10(2), 39–46. https://doi.org/10.29121/ijoest.v10.i2.2026.749 DOI: https://doi.org/10.29121/ijoest.v10.i2.2026.749
Nayar R, Ivanovic M. The indeterminate thyroid fine-needle aspiration experience from an academic center using terminology similar to that proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Cancer 2009;117(3):195-202. DOI: https://doi.org/10.1002/cncy.20029
Shuja A. History of thyroid surgery. Professional Med J 2008;15(2): 295-7. DOI: https://doi.org/10.29309/TPMJ/2008.15.02.2813
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Copyright (c) 2026 Dr. Sumana Pawar, Dr. Rajesh H. Chandan, Dr. Suwarna Siddappa Kolavi

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