DETERMINATION OF RADIOLOGICAL PARAMETERS OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS USING WINXCOM SOFTWARE IN THE ENERGY RANGE 1KeV TO 100KeV

  • Arome Aruwa Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
  • Philibus Musa Gyuk Department of Physics, Kaduna State University, Kaduna, Nigeria
  • Columbus Tobechukwu Eze Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
  • Suleiman Isah Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
  • Achor Mathias Ogwo Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
  • Ashibi Martha Ali Adejo Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria https://orcid.org/0000-0003-3914-774X
Keywords: Effective Atomic Number, Electron Density, Active Pharmaceutical Ingredient’s, Winxcom, Pharmaceutical, Mass Attenuation Coefficient

Abstract

The effective atomic number, electron density and mass attenuation coefficient of some selected active pharmaceutical ingredients such as Diclofenac Sodium, Femotidine, Alprazolam, Amiodar, Amiodarone, Ciprofloxacin, and Nimesulide have been calculated over the energy range from 1 keV to 100 GeV for total and partial photon interactions by using WinXCom. The obtained data shows that the change in mass attenuation coefficient and electron density varies with energy and chemical composition of the active pharmaceutical ingredients (API’s) in drugs. The results in the variation of photon interaction with energy and effective atomic number of the API’s in drug are shown in the logarithmic graphs.

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Published
2021-10-15
How to Cite
Aruwa, A., Gyuk, P. M., Eze, C. T., Isah, S., Ogwo, A. M., & Adejo, A. M. A. (2021). DETERMINATION OF RADIOLOGICAL PARAMETERS OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS USING WINXCOM SOFTWARE IN THE ENERGY RANGE 1KeV TO 100KeV. International Journal of Engineering Science Technologies, 5(5), 54-62. https://doi.org/10.29121/ijoest.v5.i5.2021.208