DETERMINATION OF RADIOLOGICAL PARAMETERS OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS USING WINXCOM SOFTWARE IN THE ENERGY RANGE 1KeV TO 100KeV

Arome Aruwa; Philibus Musa Gyuk; Columbus Tobechukwu Eze; Suleiman Isah; Achor Mathias Ogwo; Ashibi Martha Ali Adejo

doi:10.29121/ijoest.v5.i5.2021.208

Authors

Arome Aruwa Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
Philibus Musa Gyuk Department of Physics, Kaduna State University, Kaduna, Nigeria
Columbus Tobechukwu Eze Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
Suleiman Isah Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
Achor Mathias Ogwo Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria
Ashibi Martha Ali Adejo Department of Science Laboratory Technology, Federal Polytechnic, Idah, Nigeria https://orcid.org/0000-0003-3914-774X

DOI:

https://doi.org/10.29121/ijoest.v5.i5.2021.208

Keywords:

Effective Atomic Number, Electron Density, Active Pharmaceutical Ingredient’s, Winxcom, Pharmaceutical, Mass Attenuation Coefficient

Abstract

The effective atomic number, electron density and mass attenuation coefficient of some selected active pharmaceutical ingredients such as Diclofenac Sodium, Femotidine, Alprazolam, Amiodar, Amiodarone, Ciprofloxacin, and Nimesulide have been calculated over the energy range from 1 keV to 100 GeV for total and partial photon interactions by using WinXCom. The obtained data shows that the change in mass attenuation coefficient and electron density varies with energy and chemical composition of the active pharmaceutical ingredients (API’s) in drugs. The results in the variation of photon interaction with energy and effective atomic number of the API’s in drug are shown in the logarithmic graphs.

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