PROBIOTICS AND THEIR ATTRIBUTES IN HUMAN HEALTH THERAPY: REVIEW
Keywords:Probiotic Microorganisms, Human Health Benefits, Mechanism
There is a strong correlation between diet and human health. Research shows that a number of disease and disorders can be prevented/regulated by the use of probiotic microorganisms. Probiotics are used in the management of illnesses/disorders such as intestinal pathogenic infections, helicobacter pylori infections, urogenital infection, cancer, obesity, Type 2 diabetes, GIT, IBD and lactose intolerance among others. Probiotics may also have a direct or indirect influence to the human health by the elimination of toxins, protection against enteric microorganisms and boosting the body immune system. These benefits among others have led to the in-depth studies aiming at the understanding of specific probiotics and the mechanism involved in disease therapy. Some commonly used probiotic strains in the dairy industry include among others Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus casei, Lactobacillus reuteri, and S. boulardii. Although the mechanisms used by probiotics in disease treatment is not specifically clear, its reported that the modification of the intestinal microbiota, production of short-chain fatty acids (SCFAs) hence maintenance of the pH in digestive system, production of bacteriocin and vitamins could be among the possible mechanisms. The aim of this review paper is to highlight the benefits of probiotics in human health & infections control through the consumption of probiotic products and some mechanism involved.
Rajyalakshmi, K., et al., Benefaction of probiotics in human gastro intestinal tract. 2019.
Maldonado, N.C., et al., Identification, characterization and selection of autochthonous lactic acid bacteria as probiotic for feedlot cattle. Livestock science, 2018. 212: p. 99-110. DOI: https://doi.org/10.1016/j.livsci.2018.04.003
Figueroa‐González, I., et al., Probiotics and prebiotics—perspectives and challenges. Journal of the Science of Food and Agriculture, 2011. 91(8): p. 1341-1348. DOI: https://doi.org/10.1002/jsfa.4367
Markowiak, P. and K. Śliżewska, Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients, 2017. 9(9): p. 1021. DOI: https://doi.org/10.3390/nu9091021
Shehata, M., et al., Screening of isolated potential probiotic lactic acid bacteria for cholesterol lowering property and bile salt hydrolase activity. Annals of Agricultural Sciences, 2016. 61(1): p. 65-75. DOI: https://doi.org/10.1016/j.aoas.2016.03.001
Kerry, R.G., et al., Benefaction of probiotics for human health: A review. Journal of food and drug analysis, 2018. 26(3): p. 927-939. DOI: https://doi.org/10.1016/j.jfda.2018.01.002
Halvorsen, R., et al., The use of probiotics for patients in hospitals. A benefit and risk assessment. Opinion of the Steering Committee of the Norwegian Scientific Committee for Food Safety. VKM Report, 2009.
Amara, A. and A. Shibl, Role of Probiotics in health improvement, infection control and disease treatment and management. Saudi pharmaceutical journal, 2015. 23(2): p. 107-114. DOI: https://doi.org/10.1016/j.jsps.2013.07.001
Nova, E., et al., Immunomodulatory effects of probiotics in different stages of life. British Journal of Nutrition, 2007. 98(S1): p. S90-S95. DOI: https://doi.org/10.1017/S0007114507832983
Oelschlaeger, T.A., Mechanisms of probiotic actions–a review. International Journal of Medical Microbiology, 2010. 300(1): p. 57-62. DOI: https://doi.org/10.1016/j.ijmm.2009.08.005
Daliri, E.B.-M. and B.H. Lee, New perspectives on probiotics in health and disease. Food Science and Human Wellness, 2015. 4(2): p. 56-65. DOI: https://doi.org/10.1016/j.fshw.2015.06.002
Goh, Y.J. and T.R. Klaenhammer, A functional glycogen biosynthesis pathway in L actobacillus acidophilus: expression and analysis of the glg operon. Molecular microbiology, 2013. 89(6): p. 1187-1200. DOI: https://doi.org/10.1111/mmi.12338
Ishimwe, N., et al., The perspective on cholesterol‐lowering mechanisms of probiotics. Molecular nutrition & food research, 2015. 59(1): p. 94-105. DOI: https://doi.org/10.1002/mnfr.201400548
Lee, J.Y., et al., Proteomic and transcriptional analysis of Lactobacillus johnsonii PF01 during bile salt exposure by iTRAQ shotgun proteomics and quantitative RT-PCR. Journal of proteome research, 2013. 12(1): p. 432-443. DOI: https://doi.org/10.1021/pr300794y
Huang, Y., et al., Lactobacillus plantarum strains as potential probiotic cultures with cholesterol-lowering activity. Journal of Dairy Science, 2013. 96(5): p. 2746-2753. DOI: https://doi.org/10.3168/jds.2012-6123
Ooi, L.-G. and M.-T. Liong, Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings. International journal of molecular sciences, 2010. 11(6): p. 2499-2522. DOI: https://doi.org/10.3390/ijms11062499
Barling, P.M., Lactose tolerance and intolerance in Malaysians. IeJSME, 2012. 6(Suppl 1): p. S12-S23.
Tejero-Sariñena, S., et al., Antipathogenic activity of probiotics against Salmonella Typhimurium and Clostridium difficile in anaerobic batch culture systems: is it due to synergies in probiotic mixtures or the specificity of single strains? Anaerobe, 2013. 24: p. 60-65.
Saint-Cyr, M.J., et al., Use of the potential probiotic strain Lactobacillus salivarius SMXD51 to control Campylobacter jejuni in broilers. International journal of food microbiology, 2017. 247: p. 9-17. DOI: https://doi.org/10.1016/j.ijfoodmicro.2016.07.003
Chingwaru, W. and J. Vidmar, Potential of Zimbabwean commercial probiotic products and strains of Lactobacillus plantarum as prophylaxis and therapy against diarrhoea caused by Escherichia coli in children. Asian Pacific journal of tropical medicine, 2017. 10(1): p. 57-63. DOI: https://doi.org/10.1016/j.apjtm.2016.12.009
Islam, S.U., Clinical uses of probiotics. Medicine, 2016. 95(5). DOI: https://doi.org/10.1097/MD.0000000000002658
Chan, P.A., et al., Extragenital infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae: a review of the literature. Infectious diseases in obstetrics and gynecology, 2016. 2016. DOI: https://doi.org/10.1155/2016/5758387
Waigankar, S.S. and V. Patel, Role of probiotics in urogenital healthcare. Journal of mid-life health, 2011. 2(1): p. 5. DOI: https://doi.org/10.4103/0976-7800.83253
Iqbal, M.Z., et al., Probiotics and their beneficial effects against various diseases. Pakistan journal of pharmaceutical sciences, 2014. 27(2).
Larsen, N., et al., Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults. PloS one, 2010. 5(2). DOI: https://doi.org/10.1371/journal.pone.0009085
Karimi, G., et al., The anti-obesity effects of Lactobacillus casei strain Shirota versus Orlistat on high fat diet-induced obese rats. Food & nutrition research, 2015. 59(1): p. 29273. DOI: https://doi.org/10.3402/fnr.v59.29273
Bengmark, S., Bioecological control of inflammatory bowel disease. Clinical Nutrition, 2007. 26(2): p. 169-181. DOI: https://doi.org/10.1016/j.clnu.2006.10.001
Kobyliak, N., et al., Probiotics in prevention and treatment of obesity: a critical view. Nutrition & metabolism, 2016. 13(1): p. 14. DOI: https://doi.org/10.1186/s12986-016-0067-0
Gayathri, D. and B. Rashmi, Anti-cancer properties of probiotics: a natural strategy for cancer prevention. EC Nutrition, 2016. 5(4): p. 1191-1202.
Awaisheh, S., et al., In vitro cytotoxic activity of probiotic bacterial cell extracts against Caco-2 and HRT-18 colorectal cancer cells. Milk Science International-Milchwissenschaft, 2016. 69(7): p. 33-37.
Mayer, E.A., K. Tillisch, and A. Gupta, Gut/brain axis and the microbiota. The Journal of clinical investigation, 2015. 125(3): p. 926-938. DOI: https://doi.org/10.1172/JCI76304
Tillisch, K., The effects of gut microbiota on CNS function in humans. Gut microbes, 2014. 5(3): p. 404-410. DOI: https://doi.org/10.4161/gmic.29232
Takeda, S., et al., Antiallergic activity of probiotics from Mongolian dairy products on type I allergy in mice and mode of antiallergic action. Journal of Functional Foods, 2014. 9: p. 60-69. DOI: https://doi.org/10.1016/j.jff.2014.04.013
Palumbo, V.D., et al., The long-term effects of probiotics in the therapy of ulcerative colitis: A clinical study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2016. 160(3): p. 372-377. DOI: https://doi.org/10.5507/bp.2016.044
Szajewska, H., What are the indications for using probiotics in children? Archives of disease in childhood, 2016. 101(4): p. 398-403.
Daliri, E., D. Oh, and B. Lee, Psychobiotics; a promise for neurodevelopmental therapy. J Probiotics Health, 2016. 4: p. 1e4.
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