STUDY OF CLINICAL FEATURES AND EPIDEMIOLOGY OF COMPLICATED VIVAX MALARIA

Authors

  • Dr. Arvind Mathur Professor and Head Department of Medicine, Dr SN Medical College, India 2 Medical Officer, MDM Hospital, India
  • Dr. Mohit Kackar Medical Officer, MDM Hospital, India
  • Dr. Indu Thanvi Assistant Professor Medicine, Dr SN Medical College, India
  • Dr. Harish Agarwal JS Medicine, Dr SN Medical College, India

DOI:

https://doi.org/10.29121/granthaalayah.v7.i9.2019.556

Keywords:

Study, Clinical Features, Epidemiology

Abstract [English]

Severe and complicated malaria is defined by the World Health Organization Malaria Action Programme in June 19851 as the presence of one or more of the following conditions in a slide confirmed diagnosed case of malaria cerebral malaria, severe anemia, renal failure, pulmonary edema or adult respiratory distress syndrome, hypoglycemia, circulatory collapse or shock, spontaneous bleeding, repeated generalized convulsions, acidemia or acidosis, macroscopic hemoglobinuria, impairment of consciousness less marked than unarousable coma,, hyperparasitemia, jaundice, hyperpyrexia, and the presence of complicating or associated infections. However, severe anemia and thrombocytopenia that causes bleeding diatesis is produced by hemolysis, reduced cell deformity of parasitized and non-parasitized erythrocytes, increased splenic clearance, reduction of platelet survival, decreased platelet production, and increased splenic uptake of platelets. Though these changes can be produced by P. vivax and P. falciparum infection yet the complicated malaria has commonly been associated with P. falciparum infections.

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References

WHO Malaria Action Programme. Severe and complicated malaria. Trans Roy Soc Trop Med Hyg 1986; 80 (suppl):3-50. DOI: https://doi.org/10.1016/0035-9203(86)90407-4

Prakash Singh AK, Kumar NS, Saxena R. K: Acute renal failure in Plasmodium vivax malaria J Assoc Physicians India. 2005 Jul; 53:655;

Beg M.A., Khan R., Baig S.M., et al. Cerebral involvement in benign tertian malaria. Am J Trop Med H2002; 67:230-233. DOI: https://doi.org/10.4269/ajtmh.2002.67.230

Curlin M.E., Barat L.M., Walsh D.K., Granger D.L. Non-cardiogenic pulmonary edema during vivax malaria. Clin Infect Dis 1999; 28:1166-7. DOI: https://doi.org/10.1086/517767

Kochar DK, Saxena V, Singh N et al. Plasmodium vivax malaria. Emerg Infect Dis 2005;11(1):132-134. DOI: https://doi.org/10.3201/eid1101.040519

WHO: Severe and complicated malaria. World Health Organization, Division of Control of Tropical Diseases. Trans R Soc Trop Med Hyg 1990; 84 Suppl 2: 1-65. DOI: https://doi.org/10.1016/0035-9203(90)90363-J

World Health Organization. Severe falciparum malaria. Trans R Soc Trop Med Hyg. 2000; 94:38–40. DOI: https://doi.org/10.1016/S0035-9203(00)90300-6

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Published

2019-09-30

How to Cite

Mathur, A., Kackar, M., Thanvi, I., & Agarwal, H. (2019). STUDY OF CLINICAL FEATURES AND EPIDEMIOLOGY OF COMPLICATED VIVAX MALARIA. International Journal of Research -GRANTHAALAYAH, 7(9), 47–51. https://doi.org/10.29121/granthaalayah.v7.i9.2019.556