ANTIOXIDANT AND ANTIMICROBIAL POTENTIAL OF COCCINEA CORDIFOLIA

Saumendu Deb Roy; Suvakanta Dash; Jashabir Chakraborty

doi:10.29121/granthaalayah.v6.i9.2018.1235

Authors

Saumendu Deb Roy Bharat Technology, Uluberia, Howrah, West Bengal, India
Suvakanta Dash Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura, India
Jashabir Chakraborty Girijananda Chowdhury Institute of Pharmaceutical Science, Guwahati, Assam, India

DOI:

https://doi.org/10.29121/granthaalayah.v6.i9.2018.1235

Keywords:

Coccinea Cordifolia, Traditional Medicine, Antioxidant, Antimicrobial

Abstract [English]

In the present study, Coccinea cordifolia root was extracted with various solvents according to their increasing order of polarity and the extracts were subjected to preliminary phytochemical investigation. The extracts were then subjected to antioxidant assay using FTC, TBA, DPPH and Reducing Power assay as models and Antimicrobial assay. The Methanolic extract of the plant root has shown good antioxidant and antimicrobial activity among the extracts under study. The findings of the study here justify the traditional claim against Coccinea cordifolia root.

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References

Http://Www.Ayushveda.Com/Herbs/Coccinia-Indica.Htm#

Ganga Br, Umamaheswara Pr, Sambasiva Er, Mallikarjuna Tr, Praneeth Dvs. (2011). “Studies On Phyto Chemical Constituents, Quantification Of Total Phenol, Alkaloid Content And In-Vitro Anti-Oxidant Activity Of Coccinia Cordifolia.” Int. J. Ph. Life Sc., 2(10), 1177-1182.

Percival M. (1996). “Antioxidants”. Clin. Nutri. Insghts., 1, 1-4.

Young Is, Woodside Jv. (2001). “Antioxidants in Health and Disease”. J. Clin. Pathol., 54, 176-186. DOI: https://doi.org/10.1136/jcp.54.3.176

Bawara B, Dixit M, Chauhan Ns, Dixit Vk, Saraf Dk. (2010). “Phyto-Pharmacology of Momordica Dioica Roxb. Ex. Willd: A Review”. Int. J. Phytomed., 2, 1-9.

Ehsan O, Norhani A, Wan Zs, Abdul Ro, Syahida A, Wen K, (2011). “Antioxidant, Anti-Inflammatory and Anticancer Activities of Methanolic Extracts from Jatropha Curcas Linn”. J. Med Plants. Res., 5(1), 49-57.

Jerneja J, Robert V, Franci F. (2009). “Extraction of Phenolic Compounds from Green Walnut Fruits in Different Solvents”. Act. Agri. Slove., 93(1), 11-15.

Harborne Jb. (1998). “Phytochemical Methods, A Guide to Modern Technique of Plant Analysis”. 3rd Ed. London: Springer (India) Pvt. Ltd; 49-188.

Kokate Ck, Purohit Ap, Gokhale Sb. (2010). “Pharmacognosy”. 46th Ed. Pune: Nirali Prakashan; A1-A6.

Sreejayan N, Rao Mna. (1997). “Free Radical Scavenging by Curcuminoids”. J Pharm Pharmacol , 1997,49, 105-109.

Chang St, Wu Jh, Wang Sy, Kang Pl, Yang Ns, Shyur Lf. (2001). “Antioxidant Activity of Extracts from Acacia Confusa Bark and Heartwood”. J. Agri. Food Chem., 49, 3420-3424. DOI: https://doi.org/10.1021/jf0100907

Ramazan A, Mehmet C, Ensari F. (2001). “Protective Effects of Vitamin E, Selenium and Allopurinol Against Stress-Induced Ulcer Formation in Rats”. Turk. J. Med. Sci., 31, 199-203.

Oyaizu M. “Studies on Products of Browning Reactions: Antioxidative Activities of Products of Browning Reaction Prepared from Glucosamine”. Jpn. J. Nutr., 44, 307-315. DOI: https://doi.org/10.5264/eiyogakuzashi.44.307

Hanane E, Nadaya L, Katim A, Yahya C, Abdellah F, Brahim B, Mohammed L. (2011). “Antioxidant Activity, Phytochemical Screening, And Total Phenolic Content of Extracts from Three Genders of Carob Tree Barks Growing in Morocco”. Arabian J. Chem., 2, 321-324.

Faten Mae. (2009). “Antioxidant and Anticancer Activities of Doum Fruit Extract (Hyphaene Thebaica)”. Afr. J. Pure. App. Chem., 3(10), 197-201.

Peryasamy A, Raj K, Mahalingam K. (2010). “Phytochemical Screening and Antimicrobial Activity from Five Indian Medicinal Plants Against Human Pathogens”. Middle East J. Sci Res., 5(6), 477-482.

Jeya Sheela D, Jeeva S, Ramzan Shamila Im, Packia Lekshmi Ncj, Raja Brindha J. (2012). “Antimicrobial Activity and Phytochemical Analysis of Sanseiveria Roxburghiana Leaf”. Asian J. Plant Sci. Res., 2 (1), 41-44.

Mahesh B, Satish S. (2013). “Antimicrobial Activity of Some Important Medicinal Plant Against Plant and Human Pathogens”. World J. Agric. Sci., 4, 839-843.

Estari M, Gujjeti Rp. (2008) “Phytochemical and Antimicrobial Activity of Acmella Paniculata Plant Extracts”. J. Bio. Innov., 2(1), 17-22.

Abdullah, N., Khatun, A., (2011). “Evaluation of Phytochemical and Pharmacological Properties of Mikania Cordata (Asteraceae) Leaves”. J. Phramacog. Phytother., 3, 118-123.

Tanti B, Buragohain A K, Gurung L, Kakati D, Das Ak, Borah Sp. (2010). “Assessment of Antimicrobial and Antioxidant Activities of Dendrocnide Sinuata (Blum) Chew Leaves-A Medicinal Plants Used by Ethnic Communities Of North East India”. Ind. J. Nat. Prod. Resour., 1(1), 17-21.