INFγ, TNFα, IL-6 LEVELS IN THE PERIPHERAL BLOOD SERUM IN DIFFERENT CLINICAL COURSES OF NONSPECIFIC VULVOVAGINITIS IN ADOLESCENT GIRLS

Smailova Lazat Kenzhebekovna; Bilalova Gulshat Tursunovna; Kurmanova Almagul Medeubaeva

doi:10.29121/granthaalayah.v5.i7.2017.2147

Authors

Smailova Lazat Kenzhebekovna JSC, Astana Medical University, Republic of Kazakhstan, Astana
Bilalova Gulshat Tursunovna JSC, Astana Medical University, Republic of Kazakhstan, Astana
Kurmanova Almagul Medeubaeva Doctor of Medical Sciences, Professor Scientific Center of Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Republic of Kazakhstan, Almaty

DOI:

https://doi.org/10.29121/granthaalayah.v5.i7.2017.2147

Keywords:

Adolescent Girl, Vulvovaginitis, Immunity, Cytokines

Abstract [English]

The conducted study showed that increased production of anti-inflammatory INFγ cytokine is observed in girls and adolescents with acute nonspecific vulvovaginitis compared to the subacute course of the disease, though no adequately high production of this cytokine is practically observed in both cases. The obtained data indicate the suppression of both the cell and humoral anti-inflammatory immunity. IL-6 is responsible for the specificity and the adequacy of immunological reactions. This fact is connected primarily with the presence of multidirectional pathological changes in the immunity system.

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