THE USES OF MORINGA CAPSULES WITH NANOGOLD AS DRUG DELIVERY AND NANO-SILVER AS ANTIVIRAL FOR IMMUNE IMPROVEMENT OF COVID19 PATIENTS
DOI:
https://doi.org/10.29121/granthaalayah.v9.i11.2021.4347Keywords:
Moringa Capsule, Body Immune, Nanogold, Nano-Silver, Covid19Abstract [English]
Improving the immunity of COVID-19 patients is very important for the healing process. As is known, viral diseases, including COVID-19, cannot be treated. What can be done is to increase the body's immune system to be strong against the virus attack and weaken it. Various efforts to increase immunity are carried out, among others, with Moringa capsules containing nanogold and nano-silver. Nanogold as drug delivery and nano-silver as antiviral. A total of 64 COVID-19 patients who were treated using Moringa capsules routinely showed a significant recovery process. Clinical trial volunteers were grouped into 3 categories. The first group of positive COVID-19 asymptomatic 22 people. The second group of 24 COVID-19 positive people with mild to moderate symptoms, including experiencing fever, cough, runny nose, and weakness. The 3rd group of 18 people were COVID-19 patients with severe conditions with respiratory problems to the point of using a ventilator. The results of the clinical trial showed that the first group of Covid-19 patients recovered after consuming Moringa capsules for 1-2 weeks, the second group recovered 3-6 weeks. The 3rd group recovered 4-8 weeks. In conclusion, it is proven that Moringa capsules with nanogold and nano-silver increase the immunity of Covid-19 patients so that they survive and recover from their pain. The length of time required for recovery is different for each group. The first group recovered faster than the second group. The third group recovered the longest. It is highly recommended to use Moringa capsules with nanogold and nano-silver innovations to recover COVID-19, especially the new variants that are more easily spread.
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References
A. A. Moustafa and S. R. Mansour, (2020) "Moringa peregrina a Natural Medicine for Increasing Immunity Defense against the COVID-19 Medicinal & Aromatic Plants," no. July, pp. 1-8.
B. A. Katsnelson et al., (2013) "Comparative in vivo assessment of some adverse bioeffects of equidimensional gold and silver nanoparticles and the attenuation of nanosilver's effects with a complex of innocuous bioprotectors," Int. J. Mol. Sci., vol. 14, no. 2, pp. 2449-2483. Retrieved from https://doi.org/10.3390/ijms14022449 DOI: https://doi.org/10.3390/ijms14022449
F. K. Alanazi, A. A. Radwan, and I. A. Alsarra, (2010) "Biopharmaceutical applications of nanogold," Saudi Pharmaceutical Journal, vol. 18, no. 4. pp. 179-193. Retrieved from https://doi.org/10.1016/j.jsps.2010.07.002 DOI: https://doi.org/10.1016/j.jsps.2010.07.002
F. Zivic, N. Grujovic, S. Mitrovic, I. U. Ahad, and D. Brabazon, (2017) "Characteristics and applications of silver nanoparticles," in Commercialization of Nanotechnologies-A Case Study Approach. Retrieved from https://doi.org/10.1007/978-3-319-56979-6_10 DOI: https://doi.org/10.1007/978-3-319-56979-6_10
H. R. Sodagari, R. Bahramsoltani, M. H. Farzaei, A. H. Abdolghaffari, N. Rezaei, and A. W. Taylor-Robinson, (2016) "Tea polyphenols as natural products for potential future management of HIV infection - an overview," J. Nat. Remedies, vol. 16, no. 2. Retrieved from https://doi.org/10.18311/jnr/2016/4782 DOI: https://doi.org/10.18311/jnr/2016/4782
I. Ignatov, (2020) "Anti Inflammatory and Anti Viral Effects of Potassium ( K ) and Chemical Composition of Moringa," vol. 9, no. 2, pp. 1-7. Retrieved from https://doi.org/10.9734/ajob/2020/v9i230081 DOI: https://doi.org/10.9734/ajob/2020/v9i230081
M. A. Dkhil, A. A. Bauomy, M. S. M. Diab, and S. Al-Quraishy, (2015) "Antioxidant and hepatoprotective role of gold nanoparticles against murine hepatic schistosomiasis," Int. J. Nanomedicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687720/
M. Batory et al., (2016) "The use of liposomes in the modification of polycaprolactone fibers," J. Appl. Polym. Sci. Retrieved from https://doi.org/10.1002/app.43299 DOI: https://doi.org/10.1002/app.43299
M. Hajimonfarednejad, M. Ostovar, M. J. Raee, M. H. Hashempur, J. G. Mayer, and M. Heydari, (2018) "Cinnamon: A systematic review of adverse events," Clinical Nutrition. Retrieved from https://doi.org/10.1016/j.clnu.2018.03.013 DOI: https://doi.org/10.1016/j.clnu.2018.03.013
M. Hashem, A. E. M. Abdalla, E. R. Abdol Raouf, A. El-Shafei, S. Zaghloul, and M. K. El-Bisi, (2016) "Moringa oleifera-silver nanohybrid as green antimicrobial finishing for cotton fabrics," Egypt. J. Chem., vol. 59, no. 4. Retrieved from https://doi.org/10.21608/ejchem.2016.1200 DOI: https://doi.org/10.21608/ejchem.2016.1200
N. Khorshidian, M. Yousefi, M. Shadnoush, and A. M. Mortazavian, (2018) "An overview of β-glucan functionality in dairy products," Curr. Nutr. Food Sci. Retrieved from https://doi.org/10.2174/1573401313666170609092748 DOI: https://doi.org/10.2174/1573401313666170609092748
P. Mehrbod et al., (2009) "In Vitro Antiviral Effect of " Nanosilver " on Influenza Virus," vol. 17, no. 2, pp. 88-93. Retrieved from https://www.sid.ir/en/journal/ViewPaper.aspx?ID=144384
Q. Zheng, H. Yang, J. Wei, J. long Tong, and Y. qian Shu, (2013) "The role and mechanisms of nanoparticles to enhance radiosensitivity in hepatocellular cell," Biomed. Pharmacother. Retrieved from https://doi.org/10.1016/j.biopha.2013.04.003 DOI: https://doi.org/10.1016/j.biopha.2013.04.003
S. Francis, E. P. Koshy, and B. Mathew, (2018) "Microwave Aided Synthesis of Silver and Gold Nanoparticles and their Antioxidant, Antimicrobial and Catalytic Potentials," J Nanostruct. Retrieved from https://jns.kashanu.ac.ir/article_58580.html
S. Syamaidzar, (2020) "Review Vaksin Covid-19," no. July, pp. 0-14.
S. V. et al., (2014) "Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities," International Journal of Nanomedicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211914/
T. A. Novitasari, (2021) "The Effect of Nanogold-Nanosilver for Immune Enhancement of Drug Abuse Victims in Areas Affected by COVID-19," Int. J. Curr. Sci. Res. Rev., vol. 04, no. 01, pp. 32-39. Retrieved from https://doi.org/10.47191/ijcsrr/V4-i1-06 DOI: https://doi.org/10.47191/ijcsrr/V4-i1-06
T. Kinoshita et al., (2014) "Immuno-Electron Microscopy of Primary Cell Cultures from Genetically Modified Animals in Liquid by Atmospheric Scanning Electron Microscopy," Microsc. Microanal., vol. 20, no. 02, pp. 469-483, Apr. Retrieved from https://doi.org/10.1017/S1431927614000178 DOI: https://doi.org/10.1017/S1431927614000178
T. Murai, M. Sato, H. Nishiyama, M. Suga, and C. Sato, (2013) "Ultrastructural analysis of nanogold-labeled cell surface microvilli in liquid by atmospheric scanning electron microscopy and their relevance in cell adhesion," Int. J. Mol. Sci., vol. 14, no. 10, pp. 20809-20819. Retrieved from https://doi.org/10.3390/ijms141020809 DOI: https://doi.org/10.3390/ijms141020809
T. Taufikurohmah and D. Soepardjo, (2019) "Herpes Disease : Case Study Of Herpes Transmission In Islamic Cottage Schools," vol. 1, no. Snk, pp. 88-94. Retrieved from https://doi.org/10.2991/snk-19.2019.22 DOI: https://doi.org/10.2991/snk-19.2019.22
T. Taufikurohmah, D. Soepardjo, and H. Armadianto, (2020) "Synthesis and Characterization of Nanogold-Nanosilver Cluster Diameter Using UV-Visible Instruments and TEM Electron Microscope Transform Instruments," vol. 390, no. Icracos 2019, pp. 146-151. Retrieved from https://doi.org/10.2991/icracos-19.2020.31 DOI: https://doi.org/10.2991/icracos-19.2020.31
T. Taufikurohmah, G. M. Sanjaya, A. Baktir, and A. Syahrani, (2012) "Activity Test of Nanogold for Reduction of Free Radicals, a Pre-Assessment Utilization Nanogold in Pharmaceutical as Medicines and Cosmetics," J. Mater. Sci. Eng. B. Retrieved from https://d1wqtxts1xzle7.cloudfront.net/47682493/Journal_of_Materials_Science_and_Enginee20160731-30512-13n6177-with-cover-page-v2.pdf?Expires=1637147987&Signature=LUigmt20oVNu-fyAK85oznyMGBx44ZsbPNV8jNcvwfev2U4If~pLkixS3ccMCfohhqouusFjAt7Ku0IbVeMO7UzgC8UCXRpUs3Pj1Zh9izHZj2sTJqk7uS~5A7XM~W0KZWmwjwZEiC3vbxMRyj7aEEjN9g3c2v57pQdC-5XKQQvpMSmrhh8xAizdPCiF-L37dUgUsZQgv0fBoP-GRO1ayWJMml5DORTl7NtAtwpNXwhM2FGQXkOzL7cW~B6JRb61HKViqktvX8XbKk4yizx2TrNozSFKopNNUuwZF2642Ke2pSAS~KASguNimB7rz0jFFoa7BJNPyo0RIaQwqv2fTQ__&Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA
T. Taufikurohmah, R. Rusmini, and D. Soepardjo, (2021) "Aplication of nanogold and nanosilver to reduce rheumatic arthritis: Case study at leprosy patients," J. Phys. Conf. Ser., vol. 1869, no. 1. Retrieved from https://doi.org/10.1088/1742-6596/1869/1/012018 DOI: https://doi.org/10.1088/1742-6596/1869/1/012018
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