• Denise Cristina Rodrigues Department of Food Technology and Medicine and Nursing, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
  • Kely de Paula Correa Department of Food Technology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil
  • Hiasmyne Silva de Medeiros Department of Food Technology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil
  • Sylvia do Carmo Castro Franceschini Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil
  • Paulo Cesar Stringheta Department of Food Technology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil
  • Jane Sélia dos Reis Coimbra Department of Food Technology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil




Selenium, Lipid Profile, Oxidative Stress, Supplementation

Abstract [English]

Previous studies suggest that Brazil nut can improve the nutritional status of selenium, reduce oxidative stress, modify lipid profile, and alter inflammatory markers. A systematic review was performed to evaluate and synthesize the results of studies on the effect of Brazil nut supplementation on human health. The review was conducted according to the recommendations of the Preferred Reporting Items for reviews and was based on searches of the databases BIREME, BMC Proceedings, The British Library, The Cochrane Library, and PubMed up to December 2019. The searches also included at the databases Google Scholar and Web of Sciences. The descriptors were identified using the Health Science Descriptors system and the search strategy included the following combination of keywords: Bertholletia, protein, lipid, nutritive value, and selenium; in English and Portuguese. A total of 510 potential studies were screened, of which 25 studies were considered for this review. All studies showed that supplementation with Brazil nut in the amounts evaluated improved the selenium status in the body and had positive effects without reports of adverse effects. This systematic review indicates that Brazil nut has a beneficial effect on human health, but further studies with double-blind controlled clinical trials and larger sample sizes are needed for the validation of these effects.


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How to Cite

Rodrigues, D. C., Correa, K. de P., Medeiros, H. S. de, Franceschini, S. do C. C., Stringheta, P. C., & Coimbra, J. S. dos R. (2021). EFFECT OF BRAZIL NUT (BERTHOLLETIA EXCELSA) SUPPLEMENTATION ON HUMAN HEALTH: A SYSTEMATIC REVIEW . International Journal of Research -GRANTHAALAYAH, 9(4), 324–342. https://doi.org/10.29121/granthaalayah.v9.i4.2021.3871

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