• Türkan Turgay Sanko University, Faculty of Medicine, SANKO University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Turkey
  • Zekiye İpek Katirci Kirmaci Sanko University, Faculty of Health Science, Department of Physiotherapy and Rehabilitation, Turkey
  • Pınar Günel Karadeniz Sanko University, Faculty of Medicine, Department of Biostatistics, Turkey
  • Mehmet Baştemir Sanko University, Faculty of Health Science, Department of Nutrition and Dietetics, Turkey



Fatigue, Fibromyalgia, Insulin Resistance

Abstract [English]

The aim of this study is to examine the relationship between insulin resistance and fatigue in fi-bromyalgia. A total of 72 patients (4 males, 68 females) with fibromyalgia (FM) was investigated. Patients were divided into two groups by insulin resistance (IR), group 1; IR- (n=49), and group 2; IR+ (n=23). IR was determined using homeostasis model assessment (HOMA) formula. All subjects were evaluated with serum 25 (OH) D vitamin levels. The severity of the disease was measured with the Fibromyalgia Impact Questionnaire (FIQ); the level of fatigue was evaluated with Fatigue Severity Scale (FSS); and the pain level was evaluated with Visual Analog Scale (VAS). There were significant differences between the FIQ and FSS mean scores of two groups (IR+ and IR-), (p=0.031, p=0.005). There were no significant differences between two groups in respect to VAS and serum 25 (OH) D vitamin levels (p=0.789, p=0.875). There was no significant correlation be-tween vitamin D and FSS (IR+, r=-0.263, p=0.225; IR-, r=0.112, p=0.443), and also vitamin D and FIQ (IR+, r=-0.103, p=0.641; IR-, r=0.050, p=0.733) in both groups. There was no relationship be-tween insulin resistance and fatigue symptom in fibromyalgia patients, but it was observed that the severity of fatigue was higher in the group with insulin resistance.


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How to Cite

Turgay, T., Kirmaci, Z. İpek K., Karadeniz, P. G., & Baştemir, M. (2020). THE RELATIONSHIP BETWEEN INSULIN RESISTANCE AND FA-TIGUE SYMPTOM IN FIBROMYALGIA SYNDROME. International Journal of Research -GRANTHAALAYAH, 8(3), 271–278.