CHEMICAL FINGERPRINTING OF ROOT EXTRACTS FROM WITHANIA SOMNIFERA

Authors

  • Dr. Ragini Sikarwar Assistant Professor and HOD, Botany and Biotechnology Department, Govt. Home Science PG Lead College, Narmadapuram

DOI:

https://doi.org/10.29121/jahim.v5.i2.2025.77

Keywords:

Withania Somnifera, Ashwagandha, Chemical Fingerprinting, Phytochemical Profiling, Withanolides, Standardization, Medicinal Plants, Root Extracts

Abstract [English]

Withania somnifera (Ashwagandha) is a medicinal plant of high therapeutic value, traditionally used in Ayurveda for stress management, immune modulation, and neuroprotection. Its pharmacological potential is largely attributed to diverse phytochemicals, particularly withanolides, alkaloids, and phenolic compounds. In the present study, root extracts of W. somnifera were subjected to chemical fingerprinting using advanced analytical techniques to establish a comprehensive phytochemical profile. Standardized chromatographic and spectroscopic methods were employed to identify key bioactive constituents and to generate reproducible chemical patterns. The results revealed the presence of characteristic secondary metabolites that can serve as quality markers for authentication and standardization. This study highlights the importance of fingerprinting approaches in ensuring consistency, efficacy, and safety of herbal preparations derived from W. somnifera. The findings also provide a foundation for future pharmacological investigations and the development of standardized formulations.

References

Atteeq, M. (2022). Evaluating Anticancer Properties of Withaferin A — a Potent Phytochemical. Frontiers in Pharmacology, 13, 975320. https://doi.org/10.3389/fphar.2022.975320

Bashir, A., Nabi, M., Tabassum, N., Afzal, S., & Ayoub, M. (2023). An Updated Review on Phytochemistry and Molecular Targets Of Withania Somnifera (L.) Dunal (Ashwagandha). Frontiers in Pharmacology, 14, Article 1049334. https://doi.org/10.3389/fphar.2023.1049334

Mikulska, P., Malinowska, M., Ignacyk, M., Szustowski, P., Nowak, J., Pesta, K., … Cielecka-Piontek, J. (2023). Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review. Pharmaceutics, 15(4), 1057. https://doi.org/10.3390/pharmaceutics15041057

Wadhwa, R., Wang, J., Shefrin, S., Zhang, H., Sundar, D., & Kaul, S. C. (2024). Molecular Insights into the Anticancer Activity of Withaferin-A: The Inhibition of Survivin Signaling. Cancers, 16(17), 3090. https://doi.org/10.3390/cancers16173090

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Published

2025-10-15

How to Cite

Sikarwar, R. (2025). CHEMICAL FINGERPRINTING OF ROOT EXTRACTS FROM WITHANIA SOMNIFERA. Journal of Ayurvedic Herbal and Integrative Medicine, 5(2), 5–8. https://doi.org/10.29121/jahim.v5.i2.2025.77