Journal of Ayurvedic Herbal and Integrative Medicine

EVALUATION OF RASAYANA & YOGIC REGIMENS FOR ENDURANCE

Dr. Ashok Chopra, Dr. Anita Rani Chopra — Tue, 10 Mar 2026 00:00:00 +0000

Background:

Ayurveda describes Bala (strength) and Vyayama Shakti (exercise capacity) as indicators of vitality and endurance. Rasayana therapy and Yogic regimens are traditional methods for promoting physical and mental resilience. Contemporary sports science emphasizes physiological and psychological endurance as determinants of athletic performance. Integrating Ayurvedic Rasayana principles with yoga may enhance stamina, recovery, and adaptability to physical stress.

Objective:

To evaluate the comparative efficacy of a combined Rasayana and Yogic regimen versus a standard diet control on physical endurance, physiological recovery, and subjective fatigue among sportspersons aged 18–25 years.

Methods:

A 16-week, randomized, comparative clinical study was conducted among 60 healthy sportspersons (30 experimental, 30 control) in an Ayurvedic medical college setting. The experimental group received Ashwagandha churna (5 g twice daily with milk) and performed a daily Yogic regimen (Surya Namaskar, Nadi Shodhana, Bhastrika, and Shavasana; 45 min).

The control group maintained a regular diet without any Rasayana or yoga intervention. Physiological parameters—VO₂ max, endurance time, and heart rate recovery—were measured alongside psychological (perceived exertion, fatigue score) and Ayurvedic (Vyayama Shakti scale) indicators. Data were analyzed using SPSS and GraphPad Prism with paired/unpaired t-tests and ANOVA at p < 0.05 significance.

The following parameters defines the study:

Study Type: Comparative clinical study (Rasayana + Yogic regimen vs. control group with regular diet)
Sample Size: 60 sportspersons (30 in each group)
Age Range: 18–25 years
Duration: 16 weeks
Location: Ayurvedic medical college sports training facility
Ethical Status: Approved by institutional ethics committee
Assessment Parameters:

Physiological: VO₂ max, endurance time, heart rate recovery
Psychological: perceived exertion, fatigue score
Ayurvedic: Vyayama Shakti assessment scale

Analysis Tools: SPSS and GraphPad Prism; statistical tests—paired/unpaired t-test, ANOV

Results:

Preliminary findings showed statistically significant improvement (p < 0.05) in VO₂ max, endurance time, and recovery rate in the Rasayana–Yoga group compared with controls. Perceived exertion and fatigue scores decreased, while Vyayama Shakti levels increased, indicating enhanced physiological and psychological stamina. The control group showed marginal, non-significant improvement attributable to regular sports training alone.

Conclusion:

The combined Rasayana and Yogic regimen demonstrated measurable enhancement in endurance and recovery, validating the Ayurvedic concept of Rasayana in modern sports physiology. Further large-scale and biochemical studies are recommended to standardize protocols for sportspersons.

PLANT-MEDIATED GREEN SYNTHESIS OF FUNCTIONAL NANOPARTICLES: PHYSICOCHEMICAL CHARACTERIZATION AND BIOLOGICAL EVALUATION

Ramaiyan Kumaresen, M. Mahalekshmi, T. M. Vijayalakshmi, R. Murali — Fri, 20 Mar 2026 00:00:00 +0000

The research examines the mechanisms by which plants produce nanoparticles and the essential processes underlying green synthesis, which offers a safer alternative to chemical synthesis. The method allows for the creation of metallic nanostructures using plant-based compounds like terpenoids, polyphenols, and flavonoids. To fully understand bio-capped solid particles, you need to test them with UV-Vis, FTIR, XRD, and TEM/SEM equipment. The scientific studies show that this organism has a central metal structure that is protected by biological material that can kill certain types of cells while keeping harmful microorganisms from growing. The process creates a new way to make nanomedicine that is good for the environment by using plants. The method has problems because it can't make things on a large scale since it has trouble with materials of different sizes. The report says that scientists have made nanoparticles that are inspired by living things and will use them for research in agriculture and medicine in the real world.

AL-ENABLED COMPUTATIONAL STRATEGIES IN HERBAL DRUG DISCOVERY: MOLECULAR DOCKING, NETWORK PHARMACOLOGY, AND PREDICTIVE MODELING

Harshini R. L., Guna Kulothungan, T. M. Vijayalakshmi — Sat, 21 Mar 2026 00:00:00 +0000

The AI technology causes a big change that affects all the old ways of making herbal medicine. The evaluation study employs three scientific methodologies: molecular docking, network pharmacology, and predictive modeling, to ascertain the application of AI technology in scientific research. AI can fix structural gap problems thanks to the deep learning as a whole system and AlphaFold technology. This technology lets users look at large sets of phytochemical substance data. Systems that target multiple pathways along with show how herbal mixtures interact can help researchers find new drugs. Companies are changing ADMET research with AI-based prediction modeling because this method lets them find possible toxicity and metabolic syndrome. stability issues early in the product development process. The AI technologies link modern precision medicine methods with older ethnopharmacology methods by fixing problems with data standardization and "black-box" evaluation. The two groups work together to study the therapeutic uses of botanical materials, which helps them come up with new multi-component solutions for complicated health problems more quickly.

EXPERIMENTAL INSIGHTS INTO NEUROPROTECTIVE AND CARDIOPROTECTIVE MECHANISMS OF HERBAL BIOACTIVE COMPOUNDS

Dr. Parshaveni Balaraju, Dr. Kishore Kumar Godisela — Sat, 21 Mar 2026 00:00:00 +0000

Neurological and cardiovascular disorders are among the foremost contributors to worldwide morbidity and mortality through their shared disease mechanisms which include oxidative stress and chronic inflammation and apoptosis. Recent studies show that herbal bioactive compounds which include polyphenols and flavonoids and alkaloids have become important research subjects because their chemical properties enable them to target multiple biological pathways while causing minimal adverse effects. This study systematically examines the scientific data which supports the neuroprotective and cardioprotective functions of major phytochemicals including curcumin and resveratrol and quercetin and epigallocatechin gallate (EGCG). The chemicals achieve their primary neuroprotective effects in the central nervous system through three different mechanisms which include Nrf2/HO-1 pathway activation and NF-κB microglial activation control and Bax/Bcl-2 ratio maintenance to protect neurotransmitter from death. The cardioprotective effects of these compounds occur because they increase endothelial nitric oxide synthase (eNOS) activity and activate the PI3K/Akt signaling pathway and decrease ischemia-reperfusion (I/R) injury. The article presents evidence that cardiac and cerebral diseases interact with each other because herbal substances with multiple effects provide dual protective functions. The presence of insufficient bioavailability together with rapid metabolism results in clinical obstacles which prevent operational use of bioactives despite their strong preclinical evidence. The use of advanced drug delivery technologies which include lipid-based nanoparticles serves as the necessary method to enhance their therapeutic effectiveness. The research demonstrates that extensive clinical studies at a larger scale are required to validate the experimental models which show cardioprotective and neuroprotective effects.

GEOSPATIAL ANALYSIS IN HERBAL AND INTEGRATIVE MEDICINE: SPATIAL PATTERNS, ACCESSIBILITY, AND HEALTH OUTCOMES

Cruz García Lirios — Wed, 25 Mar 2026 00:00:00 +0000

Herbal and Integrative Medicine (HIM) has gained increasing relevance within contemporary healthcare systems due to its holistic approach and growing social acceptance. However, its spatial distribution, accessibility, and contextual determinants remain underexplored. This study proposes the use of geospatial analysis to examine the territorial patterns of Herbal and Integrative Medicine practices, including the location of service providers, availability of medicinal plants, and population-level utilization. By integrating Geographic Information Systems (GIS), spatial statistics, and health-related datasets, the analysis identifies geographic disparities, clusters of practice adoption, and relationships between environmental, socioeconomic, and cultural factors. The findings highlight the potential of geospatial approaches to support evidence-based planning, improve equitable access to integrative therapies, and inform public health strategies that recognize traditional and complementary medical systems within specific territorial contexts.