MOST NOTABLE PAPERS IN THE 2018 BIANNUAL METALS IN MEDICINE GORDON RESEARCH CONFERENCE

Authors

  • Yahia Z. Hamada Division of Natural Sciences and Mathematics, Lemoyne-Owen College, 807 Walker Avenue, Memphis, TN 38126, USA

DOI:

https://doi.org/10.29121/granthaalayah.v6.i11.2018.1142

Keywords:

Chemistry, Metals in Medicine, Gordon Research Conference, Inorganic Nanomaterials, Professor Mostafa A. El-Sayed

Abstract [English]

All accounts mentioned in this paper are for and from published data only and are referenced at the end of the report. Metals in Medicine Gordon Research Conference (GRC) started in 2002 with the effort of Professor Michael J. Clark and his collaborators and it has been held biannually since then. The most recent conference was held in Proctor Academy in Andover, NH USA. We are writing this Conference Report about its most recent and vibrant activities that occurred between June 24th, and June 29th, 2018. After an immensely productive week and with a prolific number of presentations in different subfields of metals and their involvement in medicinal diagnostics and treatments, the conference met all of its objectives, one of which was that very valuable agreements for future collaborations with at least two international researchers with knowledge of Molecular Dynamics, Density Function Theory, and Molecular Mechanics Calculations have been gained. The conference had its highest number of participants and attendees since its inception. There were 50 talks and 120 poster presentations. This report is being submitted in celebration of the 85th birth year of Professor Mostafa A. El-Sayed of the Department of Chemistry and Biochemistry at Georgia Institute of Technology.

Downloads

Download data is not yet available.

References

Park SY, Lytton-Jean AKR, Lee B, ET. Al. DNA-programmable nanoparticle crystallization. Nature 2008; 451: 553-556. DOI: https://doi.org/10.1038/nature06508

Rosi NL, Mirkin, CA. Nanostructures in Biodiagnostics. Chem. Rev. 2005; 105(4): 1547-1562.

Macfarlane RJ, Lee B, Jones MR, et al. Nanoparticle superlattice engineering with DNA. Science 2011; 334:204-208. DOI: https://doi.org/10.1126/science.1210493

Bellido E, Guillevic M, Hidalgo T. Understanding the Colloidal Stability of the Mesoporous MIL-100(Fe) Nanoparticles in Physiological Media. Langmuir 2014; 30(20) 5911-5920. DOI: https://doi.org/10.1021/la5012555

Horcajada P, Serre C, Maurin G. et al. Flexible Porous Metal-Organic Frameworks for a Controlled Drug Delivery. J. Am. Chem. Soc. 2008; 130 (21): 6774-6780.

Rojas S, Baati T, Njim L, et al. Metal–Organic Frameworks as Efficient Oral Detoxifying Agents. J. Am. Chem. Soc. 2018; 140 (30): 9581–9586.

Tang R, Jiang Z, Ray M. et.al Cytosolic delivery of large proteinsusing nanoparticle-stabilized nanocapsules. Nanoscale 2016; 8 18038-18041. DOI: https://doi.org/10.1039/C6NR07162G

Huo S, Gupta Y, Jiang Z. et. al. Fully Zwitterionic Nanoparticle Antimicrobial Agents through Tuning of Core Size and Ligand Structure. ACS Nano 2016; 10, 8732-8737. DOI: https://doi.org/10.1021/acsnano.6b04207

Mumtaz S, Wang, L-S, Hussain SZ.et al. Dopamine Coated Fe3O4 Nanoparticles as Enzyme Mimics for the Sensitive Detection of Bacteria. Chem. Comm. 2017; 53, 12306-12308.

Kim D, Zuidena JM, Kang J, Pan Y, Wu L, Warther D, Arkles B, Sailor MJ. Facile Surface Modification of Hydroxylated Silicon Nanostructures Using Heterocyclic Silane. J Am Chem Soc 2016; 138(46): 15106-15109. DOI: https://doi.org/10.1021/jacs.6b08614

Dominissini D, Nachtergaele S, Moshitch-Moshkovitz S, et al The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA. Nature 2016, 530, 441-446. DOI: https://doi.org/10.1038/nature16998

D. J. Raines, O. V. Moroz, E. V. Blagova, J. P. Turkenburg, K. S. Wilson, A.-K. Duhme-Klair. Bacteria in an Intense Competition for Iron: Key Component of the Campylobacter jejuni Iron Uptake System Scavenges Enterobactin Hydrolysis Product. Proc. Natl. Acad. Sci. U.S.A., 2016; 113(21): 5850-5855.

Selman M, Rousso C, Bergeron A, Hee Son H, Krishnan R, El-Sayes N A, Varette O, Chen A, Tzelepis F, Bell J C, Crans D C, and Diallo J-S, Multi-Modal Potentiation of Oncolytic Virotherapy by Vanadium Compounds. Molecular Therapy 2018, 26, 1, 56-69. DOI: https://doi.org/10.1016/j.ymthe.2017.10.014

Craig C. McLauchlan, Benjamin J. Peters, Gail R. Willsky, Debbie C. Crans. Vanadium-protein complexes: Phosphatase inhibitors favor the trigonal bipyramidal transition state geometries. Coord. Chem. Rev., 2015, 301-302, 163-199. DOI: https://doi.org/10.1016/j.ccr.2014.12.012

ThiMai T, Hamai A, Hienzsch A. et al. Salinomycin kills cancer stem cells by sequestering iron in lysosomes. Nature Chemistry 2017; 9, 1025-1033. DOI: https://doi.org/10.1038/nchem.2778

Chinen AB, Guan C, Mirkin CA. Spherical Nucleic Acid Nanoparticle Conjugates Enhance G-Quadruplex Formation and Increase Serum Protein Interactions. Angew Chem Int Ed Engl 2015; 54(2): 527-531. DOI: https://doi.org/10.1002/ange.201409211

Puerta DT, Cohen SM. Examination of Novel Zinc-Binding Groups for Use in Matrix Metalloproteinase Inhibitors. Inorg Chem 2003; 42(11): 3423-3430. DOI: https://doi.org/10.1021/ic026029g

Aydogan A, Koca A, Sener MK. et al. EDOT-Functionalized Calix [4] pyrrole for the Electrochemical Sensing of Fluoride in Water. Org Lett 2014; 16(14): 3764-3767. DOI: https://doi.org/10.1021/ol501635s

Gandin V, Tisato F, Dolmella A. et al. (In Vitro and in Vivo Anticancer Activity of Copper(I) Complexes with Homoscorpionate Tridentate Tris(pyrazolyl)borate and Auxiliary Monodentate Phosphine Ligands. J Med Chem 2014; 57(11): 4745-4760. DOI: https://doi.org/10.1021/jm500279x

Brabec V, Griffith DM, Kisova A. et al. Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA–2H)]. Mol Pharmaceutics 2012; 9(7): 1990-1999. DOI: https://doi.org/10.1021/mp300038f

Jeon J-W, Zhou J, Geldmeier JA. et al. Dual-Responsive Reversible Plasmonic Behavior of Core–Shell Nanostructures with pH-Sensitive and Electroactive Polymer Shells. Chem. Mater., 2016; 28 (20): 7551–7563.

Zhang S, Xiong R, Mahmoud MA. Dual-Excitation Nanocellulose Plasmonic Membranes for Molecular and Cellular SERS Detection. ACS Appl. Mater. Interfaces, 2018; 10 (21): 18380–18389.

Afratis N, Gialeli C, Nikitovic D. et al. Glycosaminoglycans: Key players in cancer cell biology and treatment. The FEBS journal 2012; 279 (7): 1177-1197. DOI: https://doi.org/10.1111/j.1742-4658.2012.08529.x

Katner SJ, Johnson WE, Peterson EJ. et al. Comparison of Metal–Ammine Compounds Binding to DNA and Heparin. Glycans as Ligands in Bioinorganic Chemistry. Inorg Chem 2018; 57(6): 3116-3125. DOI: https://doi.org/10.1021/acs.inorgchem.7b03043

Meola G, Braband H, Hernández-Valdés D. et al. A Mixed-Ring Sandwich Complex from Unexpected Ring Contraction in [Re(η6-C6H5Br) (η6-C6R6)](PF6) Inorg Chem 2017; 56(11): 6297-6301.

Gai Y, Sun L, Hui W. et al. New Bifunctional Chelator p-SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging. Inorg.

Ning Y, Tang J, Liu Y. et al. Highly Luminescent, Biocompatible Ytterbium (III) Complexes as Near-Infrared Fluorophores for Living Cell Imaging. Chem Sci 2018; 9(15): 3742-3753. DOI: https://doi.org/10.1039/C8SC00259B

[28] Zhen X, Xie C, Jiang Y. et al. Semiconducting Photothermal Nanoagonist for Remote-Controlled Specific Cancer Therapy. NanoLett. 2018; 18(2): 1498-1505. DOI: https://doi.org/10.1021/acs.nanolett.7b05292

Abramkin SA, Jungawirth U, Valiahidi SM. et al. {(1R,2R,4R)-4-Methyl-1,2-cyclohexanediamine} oxalatoplatinum(II): A Novel Enantiomerically Pure Oxaliplatin Derivative Showing Improved Anticancer Activity in Vivo. J. Med.Chem. 2010; 53 (20): 7356–7364.

Kowol CR, Miklos W, Pfaff S. et al. Impact of Stepwise NH2-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention. J. Med. Chem. 2016; 59 (14): 6739–6752.

Pati ML, Fanizza E, Hager S. et al. Quantum Dot Based Luminescent Nanoprobes for Sigma-2 Receptor Imaging. Mol. Pharmaceutics, 2018; 15 (2): 458–471.

Cunningham R, DeRose VJ. Platinum Binds Proteins in the Endoplasmic Reticulum of S. cerevisiae and Induces Endoplasmic Reticulum Stress. ACS Chem. Biol., 2017; 12 (11): 2737–2745.

Levina A, McLeod AI, Pulte A. et al. Biotransformations of Antidiabetic Vanadium Prodrugs in Mammalian Cells and Cell Culture Media: A XANES Spectroscopic Study. Inorg. Chem., 2015; 54 (14); 6707–6718. DOI: https://doi.org/10.1021/ic5028948

Gutierrez Sama S, Farenc M, Barrere-Mangote C. et al. Molecular Fingerprints and Speciation of Crude Oils and Heavy Fractions Revealed by Molecular and Elemental Mass Spectrometry: Keystone between Petroleomics, Metallopetroleomics, and Petrointeractomics. Energy Fuels, 2018; 32 (4): 4593–4605. DOI: https://doi.org/10.1021/acs.energyfuels.7b03218

Babak M, Pfaffeneder-Kmen M, Meier-Menches SM. et al. Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. Inorg Chem 2018; 57 (5): 2851–2864. DOI: https://doi.org/10.1021/acs.inorgchem.7b03210

Ngo AH, Bose S, Do LH. Intracellular Chemistry: Integrating Molecular Inorganic Catalysts with Living Systems. Chem.–Eur. J., 2018; 24(42): 10584-10594.

Chan AN, Shiver AL, Weaver WJ. Et al. Role for dithiolopyrrolones in disrupting bacterial metal homeostasis. Proc. Nat. Acad. Sci. USA, 2017; 10, 2717–2722. DOI: https://doi.org/10.1073/pnas.1612810114

Marker SC, MacMillan SN, Zipfel WR. et al. Photoactivated in Vitro Anticancer Activity of Rhenium(I) Tricarbonyl Complexes Bearing Water-Soluble Phosphines. Inorg. Chem. 2018; 57 (3): 1311–1331.

Hamada YZ. Prof. Mostafa A El-Sayed and Nanobiomedicine. Nanobiomedicine 2018; Volume 5, 1-2 DOI: https://doi.org/10.1177/1849543518785843

Downloads

Published

2018-11-30

How to Cite

Hamada, Y. Z. (2018). MOST NOTABLE PAPERS IN THE 2018 BIANNUAL METALS IN MEDICINE GORDON RESEARCH CONFERENCE. International Journal of Research -GRANTHAALAYAH, 6(11), 391–397. https://doi.org/10.29121/granthaalayah.v6.i11.2018.1142