SURGICAL MANAGEMENT OF PATIENTS DIAGNOSED WITH MALIGNANT PHYLLODES TUMOR OF THE BREAST IN THE NATIONAL ONCOLOGY INSTITUTE “DR. JUAN TANCA MARENGO” SOLCA – GUAYAQUIL
DOI:
https://doi.org/10.29121/granthaalayah.v10.i4.2022.4494Keywords:
Malignant Phyllodes Tumor, Surgical Technique, Mastectomy, Lumpectomy, Lymph Node Sampling, Breast BiopsyAbstract [English]
The aim is to establish the real relationship of incidence of the Malignant phyllodes Tumor of Breast and its effective surgical approach in patients treated at the Oncological Institute of Guayaquil, the reference center of Ecuador.
Objective: To establish the surgical management of Malignant phyllodes Tumors of Breast in the Oncological Institute of Ecuador SOLCA.
Method: An analysis of the cases diagnosed and operated in the Oncological Institute of Guayaquil SOLCA in the period September 2009 to September 2019, based on a retrospective descriptive study to determine the surgical management of phyllodes tumors is performed.
Results: Within the study period (9 years), 24 patients with Malignant phyllodes Tumor of Breast who met the admission criteria were analyzed. Two groups were established: 75% (n = 18) who left “alive” from the hospital and 25% “deceased” (n = 6). An analysis of the mortality adjusted to the surgical procedure was performed, where it can be observed that the radical mastectomy showed a survival of 82%, while the simple mastectomy and the lumpectomy, procedures chosen as the first option for the treatment of the malignant phyllodes tumor, presented a Survival less than 40%.
Conclusions: The phyllodes malignant breast tumor has a low incidence among malignant breast tumors. It seems that radical mastectomy of the breast is the best option for patients with this type of cancer, and adjuvance does not improve patient survival.
Downloads
References
Adesoye T, Neuman H.B et al. (2016). Current Trends in the Management of Phyllodes Tumors of the Breast, Annals of Surgical Oncology, 3199 – 3205. https://doi.org/10.1245/s10434-016-5314-0 DOI: https://doi.org/10.1245/s10434-016-5314-0
Diego, D. et al. (2016). Phyllodes Tumor. State of the Art, Colombian Journal of Cancerology, 20(2), 79-86. https://doi.org/10.1016/j.rccan.2015.10.001 DOI: https://doi.org/10.1016/j.rccan.2015.10.001
Firdaus, H. et al. (2017) Approaches to Phyllodes Tumours of the breast : a review article, International Surgery Journal, 4 (3),841-845. https://doi.org/10.18203/2349-2902.isj20170841 DOI: https://doi.org/10.18203/2349-2902.isj20170841
Francisco, T. G. et al. (2009). Tumor Filodes Maligno (Cystosarcoma filodes) mamario con diferenciación lipoblàstica. Estudio radiológico e histológico, Revista Española de Patología, 42 (3), 230-234. https://doi.org/10.1016/S1699-8855(09)70188-6 DOI: https://doi.org/10.1016/S1699-8855(09)70188-6
Jiménez-López, J. et al. (2013). Tumor Phyllodes, Perinatología y Reproducción Humana, 27 (2), 106-112. http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0187-53372013000200006
Juan A. Pérez et al. (2007). Tumor Filodes du mama. Características clínica e Histopatológica de 39 casos, Revista chilena de cirugía, 59(3), 185-190. https://doi.org/10.4067/S0718-40262007000300004 DOI: https://doi.org/10.4067/S0718-40262007000300004
Kamitani T, Matuso Y et al. (2014). Differentiation Between Benign Phyllodes Tumors and Fibroadenomas of the Breast on MR imaging, European Journal of Radiology, 83(8), 1344-1349. https://doi.org/10.1016/j.ejrad.2014.04.031 DOI: https://doi.org/10.1016/j.ejrad.2014.04.031
Karihtala P, Rissanen T et al. (2016). Male Malignant Phyllodes Breast Radiotherapy and Bicalutamide Treatment : Case report, Anticancer Research, 36(7), 3433-3436. https://ar.iiarjournals.org/content/36/7/3433.short
Nomura M, Inoue Y et al. (2006). A Case of Noninvasive Ductal Carcinoma Arising in Malignt Phyllodes Tumor, Racial and ethnic disparities in cancer, 13 (1), 89 – 94. https://doi.org/10.2325/jbcs.13.89 DOI: https://doi.org/10.2325/jbcs.13.89
Parfitt J.R, Armstrong C et al. (2004). In-situ and Invasive Carcinoma within a Phyllodes Tumor Associated with lymph Node Metastases, World Journal of Surgical Oncology, https://wjso.biomedcentral.com/articles/10.1186/1477-7819-2-46
Pornchai S, Chirappapha P et al. (2019). Predictive Factors of Recurrence Following Surgical Treatment of Phyllodes Tumors in Ramathibodi Hospital, Practical Radiation Oncology, 44(1), 79-142. https://doi.org/10.1016/S0960-9776(19)30418-7 DOI: https://doi.org/10.1016/S0960-9776(19)30418-7
Santos, J.A. et al. (2007). Tumor Filodes de Mama : Características clínicas, en imagen y Anatomopatologicas a propósito de 18 casos, Chilean Journal of Radiology, 13(2), 90 -97. https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-93082007000200008
Spitaleri G, Toesca A et al. (2013). Breast Phyllodes Tumor : A review of literature and a Single Center Retrospective Series Analysis, Critical Reviews in Oncology/Hematology, 88(2), 427-436. https://doi.org/10.1016/j.critrevonc.2013.06.005 DOI: https://doi.org/10.1016/j.critrevonc.2013.06.005
Sun L, zhu R et al. (2019). Coexisting DCIS and Phyllodes Breast Tumors in Young Chinese Women : Case Series, International Journal of Surgery Case Reports, 56, 13-16. https://doi.org/10.1016/j.ijscr.2019.01.045 DOI: https://doi.org/10.1016/j.ijscr.2019.01.045
Tan H, Zhang S et al. (2012). Imaging Findings in Phyllodes Tumors of the Breast, Discover This internationally Known Journal, 81(1), 62-69. https://doi.org/10.1016/j.ejrad.2011.01.085 DOI: https://doi.org/10.1016/j.ejrad.2011.01.085
Testori et al. (2015). Huge malignant Phyllodes Breast tumor : A Real Entity in a New era of Early Breast Cancer, World Journal of Surgical Oncology, 13, 81-82. https://doi.org/10.1186/s12957-015-0508-7 DOI: https://doi.org/10.1186/s12957-015-0508-7
Wang Y, Zhang Y et al. (2018). Huge Bordeline Phyllodes Breast Tumor with Repeated Recurrences and Progression Toward More Malignant Phenotype : A case report and literature review, OncoTargets and Therapy,11, 7787-7793. https://doi.org/10.2147/OTT.S171714 DOI: https://doi.org/10.2147/OTT.S171714
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Dr. Freddy Rueda Safady, Dr. Fernando Miñán Arana, Dr. Francisco Xavier Hernández Manrique, Dr. Pablo Ulloa Ochoa
This work is licensed under a Creative Commons Attribution 4.0 International License.
With the licence CC-BY, authors retain the copyright, allowing anyone to download, reuse, re-print, modify, distribute, and/or copy their contribution. The work must be properly attributed to its author.
It is not necessary to ask for further permission from the author or journal board.
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.
