TY - JOUR AU - S. M. Khair, Alaa Ibrahim AU - Khalid, Mosab AU - Allzain, Haghamad PY - 2020/01/31 Y2 - 2024/03/29 TI - EVALUATION OF RENAL FUNCTION IN SUDANESE DIABETIC AND HYPERTENSIVE PATIENTS IN SHENDI LOCALITY AT RIVER NILE STATE JF - International Journal of Research -GRANTHAALAYAH JA - Int. J. Res. Granthaalayah VL - 8 IS - 1 SE - Articles DO - 10.29121/granthaalayah.v8.i1.2020.238 UR - https://www.granthaalayahpublication.org/journals/granthaalayah/article/view/03_IJRG20_B01_3003 SP - 18-25 AB - <p>Microalbuminuria in urine is a known indicator of renal dysfunction. It has been extensively studied in the diabetes mellitus and hypertensive patients. This study was cross-sectional, descriptive case-control, hospital based, conducted, in Shendi locality at River Nile State in Northern Sudan, from March to July 2018.&nbsp; It intended to examine the effect of diabetes mellitus and hypertension on renal function. Urine and venous blood samples were collected sixty (60) volunteer subjects, thirty-five (35) of them known as diabetic and hypertensive patients as case group, twenty-five (25) healthy subjects as control group. Samples were examined for urine microalbuminuria and plasma creatinine levels. Case and control groups were compared by age, gender and exercise. Albumin/Creatinine Ratio (ACR). was also assessed. The mean microalbuminuria and mean ACR were significantly higher in case group (38.304mg/dl, (6.8226) mg/mmol) compared to control group (13.020mg/dl, 2.4512) mg/mmol.), with statistically significant P. value (0.007) and (0.000) respectively. &nbsp;There was statistically insignificant variation of the means of plasma creatinine between case and control groups (0.88, 0.948) mg/dl with P. value of (0.285). The present study concluded that diabetes and hypertension were associated with microalbuminuria and renal dysfunction.</p> ER -