THE CAUSAL LINK BETWEEN VACCINATION ADJUVANTS AND AUTISM

Authors

  • Thomas Prevenslik Researcher, QED Radiations, Berlin, Germany

DOI:

https://doi.org/10.29121/granthaalayah.v7.i6.2019.805

Keywords:

Adjuvants, Autism, Nanoparticles, Planck Law, Quantum Mechanics, UV, Vaccinations

Abstract [English]

Adjuvants essential in vaccines to stimulate activation of the immune system comprise submicron (< 100 nm) nanoparticles (NPs) of aluminum hydroxide that upon vaccine injection cross the blood-brain-barrier (BBB) and because of their low solubility may remain in the brain for an extended time. Despite over a century of use, the mechanism underlying the stimulation of the immune system by adjuvants has not been understood. Solar UV can optically stimulate most immune systems in the skin, but solar UV is not available inside the brain. By the process of simple QED, the NPs lacking heat capacity by the Planck law conserve heat from brain tissue by emitting UV radiation instead of increasing in temperature. Hence, the causal link between vaccination adjuvants and autism is UV stimulation of the immune system from constituent NPs that cross the BBB. But the UV also damages the DNA of brain tissue and increases the pro-inflammatory interleukin (IL-6) cytokine levels common in autism patients. Pre-vaccination enzyme-linked immunosorbent assay (ELISA) tests of IL-6 level including UV blood irradiation (UBI common in immune-modulating therapy are suggested to determine if a patient will have an adverse vaccination response. Patients having high IL-6 levels are not recommended for vaccination.

Downloads

Download data is not yet available.

References

Donaldson K, Stone V. 2003 Current hypotheses on the mechanisms of toxicity of ultrafine particles. Ann Ist Super Sanita  39: 405-410.

Donaldson K. 2003 The biological effect of coarse and fine particulate matter. Occu Environ Med 60 : 313-314. DOI: https://doi.org/10.1136/oem.60.5.313

Mroz RM, Schins RPF, Li H, Jimenez LA, Drost EM, et al. 2008 Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways. 2008; Eur Respir J.  31: 241–251. DOI: https://doi.org/10.1183/09031936.00006707

Cheng Y, Samia AC, Meyers JD, Panagopoulos I, Fei B, Burda C. 2008; Highly Efficient Drug Delivery with Gold Nanoparticle Vectors for in Vivo Photodynamic Therapy of Cancer. 2008 J. Am. Chem Soc. 130:10643–10647 DOI: https://doi.org/10.1021/ja801631c

Prevenslik T. 2010; DNA damage by Nanoparticles. Proceedings of ASME2010 First Global Conference on Nano Engineering for Medicine and Biology, NEMB2010, Houston, TX, USA, February 7-10.

Prevenslik T. 2017; Cancer by UV radiation from nanoparticles in GM food. Integr. Cancer Sci. Therap. 4(1): 2-4. DOI: https://doi.org/10.15761/ICST.1000222

El-Hussein A. 2016 Study DNA Damage after Photodynamic Therapy using Silver Nanoparticles with A549 cell line. J Nanomed. Nanotechnol Eur Respir J. 7:1

O’Rourke B. 2007; Mitochondrial ion channels. Annual Review of Physiology; 69: 19-49. DOI: https://doi.org/10.1146/annurev.physiol.69.031905.163804

Mitchell, P. 1961; Coupling of phosphorylation to electron and hydrogen transfer by a chemiosmotic type of mechanism. Nature; 191: 144–148. DOI: https://doi.org/10.1038/191144a0

Prevenslik T. 2019 ATP by Endogenous UV Radiation. www.nanoqed.org, 2019.

Shaw CA, Tomljenovic L. 2013; Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity. Immunol Res; 56: 304–316.

Kulms D, Poppelmann B, Schwarz T. 2000; Ultraviolet Radiation-induced Interleukin 6 Release in HeLa Cells Is Mediated via Membrane Events in a DNA Damage-independent Way. J Biological Chem; 20: 15060–15066. DOI: https://doi.org/10.1074/jbc.M910113199

Pelton BK, Hylton W, Denman AM. 1992 Activation of IL-6 production by UV irradiation of blood mononuclear cells from patients with systemic lupus erythematosus. Clin. Exp. Immunol; 89: 251-254. DOI: https://doi.org/10.1111/j.1365-2249.1992.tb06940.x

Mold M, Umar D, King A, Exley C. 2018 Aluminium in brain tissue in autism. J. Trace Elements Medicine Biology; 46: 76–82. DOI: https://doi.org/10.1016/j.jtemb.2017.11.012

Yang CJ, Liu CL, Sang B, Zhu XM, Du XJ. 2015; The Combined Role of Serotonin and Interleukin-6 as Biomarker for Autism. Neuroscience; 284: 290–296. DOI: https://doi.org/10.1016/j.neuroscience.2014.10.011

Wei LW. 2011; IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation. J. Neuroinflammation; 8: 52-55.

Wu X, Hu X, Hamblin MR. 2016; Ultraviolet blood irradiation: Is it time to remember “the cure that time forgot”. J Photochem Photobiol B.; 157: 89–96. DOI: https://doi.org/10.1016/j.jphotobiol.2016.02.007

Deeg HJ. 1988; Ultraviolet irradiation in transplantation biology. Manipulation of immunity and immunogenicity. Transplantation.; 45:845–851. DOI: https://doi.org/10.1097/00007890-198805000-00001

Arlett CF, Lowe JE, Harcourt SA, Waugh AP, Cole J, Roza L, Diffey BL, Mori T, Nikaido O, Green MH. 1993; Hypersensitivity of human lymphocytes to UV-B and solar irradiation. Cancer research; 53: 609–614.

Downloads

Published

2019-06-30

How to Cite

Prevenslik, T. (2019). THE CAUSAL LINK BETWEEN VACCINATION ADJUVANTS AND AUTISM. International Journal of Research -GRANTHAALAYAH, 7(6), 288–295. https://doi.org/10.29121/granthaalayah.v7.i6.2019.805