A COMPARITIVE VIEW OVER THE SYNTHESIS OF SCHIFF BASE LIGANDS AND METAL COMPLEXES BY CONVENTIONAL AND SOLVENT FREE ROUTES

  • Deeksha Sharma Department of Chemistry, Government Madhav Science College, Ujjain, M.P., India
  • Prof. Arpan Bhardwaj Department of Chemistry, Government Madhav Science College, Ujjain, M.P., India
Keywords: Salicylidene Amino Acids, 1,10- Phenanthroline, Thiourea, Azomethine

Abstract

In the present paper, synthesis of Schiff base ligands and the metal complexes are studied and compared by conventional and solvent free route. The synthesis of Schiff base ligands of amino acids (Glycine, Phenylalanine and Tyrosine) with salicylaldehyde and their mixed ligand ternary Cu(II) complexes are discussed. Other ligands are used in co-ordinaion with the schiff base is 1,10- Phenanthroline/thiourea  in equimolar ratio. The environmentally efficient and modern developed method for synthesis is the solid state synthesis of salicylidene amino acids through pestle mortar synthetic procedure. This method is compared with the conventional method that require refluxing the reactant mixture for hours in an organic solvent, here ethanol. The complexes are characterized by spectral techniques IR spectroscopy and UV spectroscopy. The investigations concluded that the pestle mortar assisted method is very rapid , simple and economic for the preparation of  ligands and complexes as well. The Antimicrobial studies were also performed for the complexes. The spectral data for the ligands and complexes obtained from either method, conventional and solventless procedure are in good agreement with one another. The azomethine bonding(-CH=N-) between salicylaldehyde amino acids based Schiff bases is described by the IR spectral peak around 1600 cm-1.

                                     

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References

K. A. Maher; S. R. Mohammed, “Metal complexes of schiff base derived from salicylaldehyde – a review”, International Journal of Current Research and Review, 7 (2), 2015.

C. K. Jorgensen, “Comparative Ligand Field Studies for Vanadium(IV), Titanium(III), Molybdenum(V) and other Systems with one d-Electron” Journal of Acta Chem. Scadinavica, 11,1957, 73 . DOI: https://doi.org/10.3891/acta.chem.scand.11-0073

M. Calligaris, G. Nardin , L. Randaccio , Coordination Chemistry Review, 7, 1972, 385 . DOI: https://doi.org/10.1016/S0010-8545(00)80018-1

M. B. Ferrari; S. Capacchi; G. Pelosi; G. Reffo; P. Tarasconi; R. Albertini; S.Pinelli; P. Lunghi, “Synthesis, structural characterization and biological activity of helicin thiosemicarbazone monohydrate and a copper(II) complex of salicylaldehyde thiosemicarbazone”, Journal of Inorganica Chimica Acta, 1999, 286, 134 . DOI: https://doi.org/10.1016/S0020-1693(98)00383-1

S. Kumar; D. N. Dhar; P. N. Saxena, “Applications of metal complexes of Schiff bases-A review”, Journal of Scientific & Industrial Research, Vol. 68, 2009, 181-187.

K. Singh; M. S. Barwa; P. Tyagi, “Synthesis and characterization of cobalt(II), nickel(II), copper(II) and zinc(II) complexes with Schiff base derived from 4-amino-3-mercapto-6-methyl-5-oxo-1,2,4-triazine” , Europian Journal of Medicinal Chemistry, 2007, 42, 394 . DOI: https://doi.org/10.1016/j.ejmech.2006.10.016

P.G. Cozzi, “Metal-Salen Schiff base complexes in catalysis: Practical aspects”, Chemical Society Review, 2004, 33, 410. DOI: https://doi.org/10.1039/B307853C

S. Chandra; J. Sangeetika, “EPR and electronic spectral studies on Copper(II) complexes of some N-O donor ligands”, Journal of Indian Chemical Society, 2004, 81, 203 .

Md. S. Ali; Md. K. Zahan; Md. M. Haque; Md. A. Alim; Md. M. Alam; J. A. Shompa; M. S. Islam, “Mixed Ligand Complexes of Co(II) and Ni(II) Containing Organic Acids and Amine Bases as Primary and Secondary Ligands” , International Journal of Materials Science and Applications, 4(4), 2015, 225-228, ISSN: 2327-2635. DOI: https://doi.org/10.11648/j.ijmsa.20150404.11

A. C. Tella; I. Y. Aaron, “Syntheses And Applications of Metal-Organic Frameworks Materials: A Review”, Acta Chimica Pharmaceutica Indica, 2(2), 2012, 75-81, ISSN 2277-288X.

Prabakarakrishnan R., Manoranjitham S. And Geetha Kannappan, “Synthesis Of Copper (II) Complexes Using Pentadentate schiff Base Ligand By Eco Friendly Solventless Method And Its Antimicrobial Activities”, vol.3, Issue-9, 2014, 1286-1299, ISSN 2277– 7105.

K.R. Sangeetha Gowda, H. S. Bhojya Naik, B. Vinay Kumar, C.N. Sudhamani, “Environmentally benign synthesis of NO donar Schiff base and their Copper(II) complex: DNA binding and Photonuclease Studies” , American Journal of PharmTech Research, 3(6), 2013 ISSN: 2249-3387.

Dr. A. Xavier, N. Srividhya, “Synthesis and Study of Schiff base Ligands”, IOSR Journal of Applied Chemistry, ISSN: 2278-5736.Vol. 7, Issue 11, 2014 06-15. DOI: https://doi.org/10.9790/5736-071110615

S. Chandralekha, G. Chandramohan, “Synthesis, Characterisation and Thermal Analysis of Cu(II) Complexes with 2,2’-bipyridyl and 1,10-phenanthroline”, African Journal of Pure and Applied Chemistry, ISSN 1996-0840, Vol. 8(10), 2014,162-175. DOI: https://doi.org/10.5897/AJPAC2014.0592

A guide to sensitivity testing: Report of working party on antibiotic sensitivity testing of the British Society for Antimicrobial Chemotherapy. Journal of Antimicrobial Chemothrapy, 27, 1991, 1-50.

D. T. John, H. J. James, Antimicrobial Susceptibility testing: General Considerations. Manual of Clinical Microbiology, 7th edition, P.R Murray, E.J Baron, M.A Pfaller, F.C Tenover, American Society for Microbiology, Washington DC, 1999, 1469-1473.

Published
2017-12-31
How to Cite
Sharma, D., & Bhardwaj, P. A. (2017). A COMPARITIVE VIEW OVER THE SYNTHESIS OF SCHIFF BASE LIGANDS AND METAL COMPLEXES BY CONVENTIONAL AND SOLVENT FREE ROUTES. International Journal of Engineering Technologies and Management Research, 4(12), 107-117. https://doi.org/10.29121/ijetmr.v4.i12.2017.603