MONTE CARLO SIMULATION IN INTERNAL RADIOTHERAPY OF THYROID CANCER
Thyroid radiotherapy is a cancer therapy that is treated by giving radioactive I-131 in Thyroid gland. This cancer is at the ninth from ten of common malignant cancer. A man has higher risk to get Thyroid cancer than a woman has. This organ is lain near human neck. This research aim was to simulate particle track of radiation I-131 and determine an absorbed dose and effective dose in Thyroid and other organs around Thyroid such as Brain, Lung and Cervical vertebrae. The simulation and calculation used Monte Carlo method operated by MCNPX software. Geometry of Thyroid and other organs used ORNL MIRD phantom geometry. From the results, it shown that particle track of radiation was distributed at Thyroid while several particles radiated other organs. The absorbed dose in Thyroid and other organs increased every rising activity of I-131 used, but the absorbed dose in other organs was less than in Thyroid. Radiation effect for damage cancer in Thyroid was shown by an effective dose which it increased every rising activity of I-131 used and the maximum effective dose was at 200 mCi activity of I-131. Although the effective dose in Thyroid increased, the effective dose in other organs like Brain, Lung and Cervical vertebrae was still less than in Thyroid so that the use of I-131 each activity did not really influence other organs around Thyroid.
Sjamsuhidajat R and De Jong W. 2005. Sistem Endokrin: Buku Ajar Ilmu Bedah 2nd edition. Kedokteran EGC.
Lukitto P, et all. 2004. Protokol Penatalaksanaan Kanker Tiroid. PERABOI Bandung.
Tjindarbumi. 1995. Karsinoma Tiroid. Binarupa Aksara Jakarta.
American Thyroid Association. 2005. Radioactive Iodine Use for Thyroid Diseases. Available at: www.thyroid.org. Access on: Juni 10th 2016.
Monte Carlo Team. 2000. MCNP A General Monte Carlo N-Particle Transport Code Version 5 Volume I: Overview and Theory. Los Alomos National Laboratory.
Cecen Y. 2013. Monte Carlo Radiation Transport in External Beam Radiotherapy. Bitlis Eren Univ J Sci and Technol.
Krstic, Dragana, et all. 2014. MCNP Sinulation of the Dose Distribution in Liver Cancer Treatment for BNC Therapy. Central European Journal of Physics. DOI: https://doi.org/10.2478/s11534-014-0507-2
Agita, R. 2011. Simulasi Penentuan Dosis Serapan Pada Brachytherapy Prostat Menggunakan Software MCNP5. Universitas Sebelas Maret. Surakarta.
M. Cristy. 1980. Mathematical Phantom Representing Children of Various Ages for Use in Estimates of Internal Dose. Oak Ridge National Laboratory.
S. Wiryosimin. 1995. Mengenal Asas Proteksi Radiasi. Institut Teknologi Bandung.
R. H. Clarke. 2011. Evaluation of ICRP Recommendations 1977, 1990 and 2007. Nuclear Energy Agency (NEA).
Copyright (c) 2016 Hammam Oktajianto, Evi Setiawati
This work is licensed under a Creative Commons Attribution 4.0 International License.
License and Copyright Agreement
In submitting the manuscript to the journal, the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
- That it is not under consideration for publication elsewhere.
- That its release has been approved by all the author(s) and by the responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
Authors who publish with International Journal of Engineering Technologies and Management Research agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
For More info, please visit CopyRight Section